Never doubt that a small group of thoughtful committed citizens can change the world. Indeed, it is the only thing that ever has.
-- Margaret Mead
Certainly the original neo-cons qualified as a small group of committed citizens. Would you call them "thoughtful"? (I don't know. Fanatical, maybe.) But they certainly did change the world - for the worse. Is it still possible for a small group to change it for good? I don't know. I hope so.